Impact of Right Ventricular Pressure Overload on Myocardial Stiffness Assessed by Natural Wave Imaging
2025
· Maelys Venet, Aimen Malik, Samantha Gold
et al.
· JACC: Cardiovascular Imaging
Product
LabChart
A highly mobile adeno-associated virus targeting vascular smooth muscle cells for the treatment of pulmonary arterial hypertension
2025
· Yoojin Kim, Yeongju Yeo, Minju Kim
et al.
· Nature Biomedical Engineering
A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors
2025
· Umberto Cillo, Caterina Lonati, Alessandra Bertacco
et al.
· Nature Communications
A soft multimodal optoelectronic array interface for multiparametric mapping of heart function in vivo
2025
· Nathaniel Quirion, Micah Madrid, Jialin Chang
et al.
· Science Advances
Area
Animal > Cardiovascular
Product
PowerLab
Multiparametric investigation of cardiac physiology is crucial for the diagnosis and therapy of heart disease. However, no method exists to simultaneously map multiple parameters that govern cardiac (patho)physiology from beating hearts in vivo. Here, we prese…
A ventral pallidum-locus coeruleus-lateral hypothalamus pathway modulates brain arousal in freely behaving and isoflurane-anesthetized male mice
2025
· Xiang-Ying Xu, Yue Xiao, Xu Liu
et al.
· Nature Communications
A wireless optogenetic setup in freely moving mice for evaluation of cortical spreading depolarization in a chronic disease model
2025
· Annika Köhne, Simeon Helgers, Bettina Kewitz
et al.
· Journal of Neuroscience Methods
AAV9-mediated MYBPC3 gene therapy with optimized expression cassette enhances cardiac function and survival in MYBPC3 cardiomyopathy models
2025
· Amara Greer-Short, Anna Greenwood, Elena Leon
et al.
· Nature Communications
An injectable conductive hydrogel for closed-loop and robot-assisted rehabilitation via stretchable patch-type electrodes
2025
· Subin Jin, Heewon Choi, Donghee Son
et al.
· Nature Protocols
Anisotropic hydrogel microelectrodes for intraspinal neural recordings in vivo
2025
· Sizhe Huang, Ruobai Xiao, Shaoting Lin
et al.
· Nature Communications
Area
Animal > Neuroscience
Product
PowerLab
Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure
2025
· Sophie Shen, Tessa Werner, Samuel Lukowski
et al.
· Nature Communications
Area
Animal > Cardiovascular
Product
LabChart
Abstract Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across developmental lineages. Here, we engineer barcoded induced pluripotent stem cells to generate an…